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21 topics: 130 hours
Cambridge CAIE 0610
100% OnlineBrowse all 21 topics covered across IGCSE Level, with resources structured to guide your learning throughout the year.
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Denotes significant gaps in understanding of key concepts within the topic.
Indicates a solid understanding of the topic, with some areas still requiring improvement.
Shows a strong command of the topic and exam-level readiness.
Learn how Cambridge IGCSE Biology (0610) is assessed across the IGCSE qualification.
Paper 1
Multiple Choice (Core)
Paper 2
Multiple Choice (Extended)
Paper 3
Theory (Core)
Paper 4
Theory (Extended)
Paper 5
Practical Test
Paper 6
Alternative to Practical
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This subject is generally considered one of the more content-heavy sciences at this level, since it spans 21 topics ranging from cell biology to ecology and genetics. Many students find topics like Coordination and Response, Inheritance, and Biotechnology and Genetic Modification challenging because they require connecting abstract processes to real biological systems. Breaking the syllabus into manageable topic-by-topic study, supported by diagrams and past paper practice, makes the volume of content far more approachable.
Paper 5 involves a hands-on practical examination where you carry out experiments and record real observations under exam conditions, while Paper 6 is a written paper that tests the same practical skills, like planning experiments and interpreting data, without requiring physical lab access. Schools choose which route their candidates take based on lab availability, so it’s worth confirming with your school or exam centre which paper you’ll be sitting.
It has up to 6 papers depending on your tier and practical route. Core candidates sit Paper 1 (Multiple Choice) and Paper 3 (Theory), while Extended candidates sit Paper 2 (Multiple Choice) and Paper 4 (Theory). All candidates also complete either Paper 5 (Practical Test) or Paper 6 (Alternative to Practical), depending on what their school offers.
Topics like Transport in Plants, Transport in Animals, Gas Exchange in Humans, and Coordination and Response rely heavily on labelled diagrams, since Cambridge frequently tests your ability to identify structures and explain their function together. Practising drawing and labelling key diagrams from memory, rather than just recognising them in a textbook, is one of the most effective ways to prepare for these questions.
Whether you’re sitting Paper 5 or Paper 6, practical skills are tested through your ability to follow methodical steps, record accurate observations or measurements, and evaluate the reliability of an experiment. The best preparation is working through past practical-style questions, paying close attention to command words like “describe” and “explain,” since vague observational language often costs marks even when the science is correct.
The Freemium Plan provides limited access to Interactive Videos and Diagnostic Reports for introductory chapters only. The Premium Plan unlocks all 21 topics, including full access to Interactive Videos, downloadable Revision Notes, Diagnostic Reports for every chapter, and additional Tutor Credits to generate Testpapers or get feedback from a Subject Tutor.